WHAT’S HAPPENING?

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Margarita Correa
13/Apr/2020

Even though there’s no proven scientific evidence of supplements to treat Coronavirus, why not support our immune system!

Diet and nutrition invariably influence the immune system competence and determine the risk and severity of infections.

The macronutrients, micronutrients, and phytonutrients in diet, mainly the fruits and colorful vegetables, generally promote healthy immune responses.

These micronutrients and phytonutrients provide the antioxidants and the anti-inflammatory nutrients, including beta-carotene, vitamin C, vitamin E, and polyphenolic compounds, which modulate the immune functions.

The anti-inflammatory strategy, either by foods, nutrients, or medicines, is a viable option.

Vitamin C

Vitamin C is an essential nutrient with several roles in your body. It’s a potent antioxidant, meaning it can neutralize unstable compounds in your body called free radicals and help prevent or reverse cellular damage caused by these compounds.

It’s also involved in a number of biochemical processes, many of which are related to immune health.

Dose: Vitamin C 1,000 – 2,000 mg a day.

Vitamin D3

The risk of viral infections can be reduced by vitamin D. The related mechanisms comprised of stimulation of defensins and cathelicidins that can decrease the replication of virus and increase levels of anti-inflammatory cytokines, as well as decreasing concentrations of pro-inflammatory cytokines that induce inflammation-related pneumonia.

While the natural source of vitamin D is from sunlight exposure, some dietary sources can provide a certain amount of vitamin D, including the fortified cereals and milk.

Dose: 1,000 – 5,000 units per day. Highest dose considered for Vitamin D deficiency.

Selenium

As the integral part of several selenoproteins, including the glutathione peroxidases and thioredoxin reductases, selenium has a critical role in the defense against viral infection through its antioxidant, redox signaling, and redox homeostatic contributions.

Selenium deficiency is associated with increased pathogenicity of several virus infections.

In the deficient state, the selenium supplementation is helpful for the prevention and treatment of viral infections.

Dose: 100 – 200 mcg a day. Higher dose increases risk of toxicity.

Zinc

Zinc is an essential micronutrient with the crucial contributions to most enzymatic functions and the transcription regulations in the human body.

Zinc is essential for normal function and development of cells regulating nonspecific immunity, including natural killer cells and neutrophils.

Research has shown that zinc has antiviral effects; it improves immune responses and suppresses viral replication.

Dose: 15 – 30 mg a day.

Don’t forget to maintain a good immune system eat nutritious foods, including vegetables and fruits, stay active performing daily exercise routine, and improve the quality of your sleep.


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Margarita Correa
30/Jan/2020

Micronized Purified Flavonoid Fraction (Diosmin) is a natural compound with a wide range of biological activity, e.g., it improves lymphatic drainage, supports microcirculation, and increases venous tone, and venous elasticity, hence, it is applied in the pharmacotherapy of chronic venous disorders (CVD).

Diosmin administration modulates pro-inflammatory as well as pro- and anti-angiogenic mechanisms in CVD pathology.

The main goal of micronized purified flavonoid fraction (MPFF) of diosmin and hesperidin is to eliminate the symptoms of CVD (venous pain, fatigue, etc). MPFF of diosmin and hesperidin has a good effect on the treatment of venous edema and venous ulcer too. Many papers prove its effectiveness in the experiment and the microcirculation. The other indications for MPFF of diosmin hesperidin are a hemorrhoidal disease and the accessory treatment of lymphedema.

As a pharmacological vasoactive agent, diosmin can protect CVD patients against edema progression by inhibition of inflammatory pathways, simultaneously influencing pro-angiogenic/anti-angiogenic balanced by an increase of anti-angiogenic factor and reducing the level of pro-angiogenic factors.

The general level of evidence supports the recommendation that the use of medical therapy with Micronized Purified Flavonoid Fraction (MPFF) has beneficial outcomes without serious adverse events.

The Micronized Purified Flavonoid Fraction (MPFF) it is derived from the rinds of oranges and is categorized as a medical food and not as a drug, and maybe a particularly attractive therapy for many chronic venous disease patients because of its favorable safety profile.

DioVasc™ contains well-researched, citrus-based flavonoids in a unique micronized form for enhanced absorption and bioavailability. Research suggests that these compounds support healthy veins, capillaries, and blood flow; promote healthy lymphatic drainage; and enhance antioxidant activity; and support healthy eicosanoid metabolism. More recent research suggests that the components in DioVasc also support blood glucose metabolism.*

Dowload Reference Sheet

References:

1.Batchvarov I.V., Batselova M.G., Damyanov I.I. One-year diosmin therapy (600 mg) in patients with chronic venous insufficiency—results and analysis. J. Biomed. Clin. Res. 2010;3:51–54

2.Shishlo VK, et al. Mechanisms of antioedemic effect of bioflavonoids in the experiment. Angiol Sosud Khir. 2013.

3.Bush R, et al. Recommendations for the medical management of chronic venous disease: The role of Micronized Purified Flavanoid Fraction (MPFF). Phlebology. 2017.

4.Feldo M, etal. Effect of Diosmin Administration in Patients with Chronic Venous Disorders on Selected Factors Affecting Angiogenesis. Molecules. 2019.


Margarita Correa
19/Oct/2019

Now you can watch the video of Margarita Correa MD presenting along side with Karen Herbst, MD, PhD, John Bartholomew, MD and Karen Beltran on Saturday, April 9 2016 Panel Discussion FDRS 2016 informing on Diagnosis and Treatment of Lipedema.

The FDRS 2016 Conference: Living with Lipedema and Dealing with Dercum’s was on April 8-10, 2016 at the Marriott St. Louis Airport hotel in St. Louis, MO. Keynote speaker is world renowned Fat Disorder expert, Karen L. Herbst, MD, PhD. Topics to include surgical and non-surgical treatment options in managing both Lipedema and Dercum’s Disease.


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Margarita Correa
30/Jan/2018

ICG lymphography is a study of the superficial lymphatics, not a treatment, helps define lymphatic dysfunction and delineate individualized lymphedema treatment. This study also helps visualize lymphedema in the asymptomatic limb. Superficial lymphatics accounts for 70% of the lymphatic system.


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